Paliperidone Injection Protocol

In this problem, we are looking at the administration of paliperidone, which is an atypical antipsychotic often given as a long-acting injection. We need to identify the correct statement Nurse Anne should make to her patient, Ken.

Let's evaluate each option carefully by looking at standard nursing protocols for this specific medication.

The first option suggests firmly massaging the injection site. For long-acting intramuscular injections like paliperidone palmitate, massaging the site can alter the absorption rate of the medication and is generally contraindicated. So, we can rule this one out.

The second option claims peak effectiveness is reached in thirteen days. In reality, for paliperidone palmitate, the median time to peak plasma concentration varies slightly but is usually closer to thirteen days for the initial doses. However, we must see if another statement is more definitive of the protocol.