Glipizide interaction with drinks

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A nurse is teaching a client who has diabetes mellitus and a new prescription for glipizide. The nurse should teach the client to avoid which of the following drinks while taking this medication? (A) Grapefruit juice (B) Milk (C) Alcohol (D) Coffee

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Step by Step Written Solution

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Step 1

In this pharmacology question, we are asked to identify which drink a nurse should advise a client to avoid while taking glipizide for diabetes mellitus.

Medication Safety Analysis

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Step 2

Let's look at the medication first. Glipizide is a sulfonylurea used to treat Type 2 diabetes by stimulating the pancreas to release more insulin.

Glipizide (Sulfonylurea)

* Class: Antidiabetic agent

* Action: Stimulates insulin secretion

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Step 3

Now, let's look at the drink options provided to see how they might interact with this specific drug class.

OptionContext
Grapefruit juiceCommonly interacts with statins or calcium channel blockers
MilkRich in calcium and protein, generally safe
AlcoholCan cause severe hypoglycemia and disulfiram-like reactions
CoffeeContains caffeine, may affect blood sugar but not a primary contraindication
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Step 4

The critical interaction for sulfonylureas like glipizide involves alcohol. First, alcohol can potentiate the hypoglycemic effect of the medication, leading to dangerously low blood sugar levels.

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About This Question

Subject
Nursing
Topic
Pharmacology
Difficulty
Medium
Question Type
Multiple Choice

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