Genetic Screening for Cancer

BiologyGenetics and OncologyMedium

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Genetic screening may be indicated for individuals who have a family history of which neoplasm? A) Leukemia B) Liver cancer C) Breast cancer D) Multiple myeloma

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Hello! Let's solve this question about genetic screening and family history of neoplasms.

Genetic screening and Family History

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Step 2

The question asks which of these neoplasms, or cancers, would indicate a need for genetic screening if there is a family history.

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Step 3

First, let's understand what genetic screening is used for in oncology.

Defining Genetic Screening

Genetic screening is used to identify individuals with an inherited predisposition to specific cancers.

Most cancers are sporadic, but some have strong hereditary links through specific gene mutations.

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Step 4

Let's evaluate our options one by one to see which is most commonly associated with hereditary syndromes.

OptionHereditary Link?
LeukemiaRarely strictly hereditary
Liver cancerOften linked to environmental factors
Breast cancerStrong link via BRCA 1 and 2
Multiple myelomaLargely sporadic
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Step 5

Breast cancer is one of the most well-known examples of a cancer with highly predictive genetic markers.

Focus: Breast Cancer

A family history of breast cancer often indicates testing for mutations in the BRCA 1 and BRCA 2 genes.

BRCA1 / BRCA2 MutationsIncreases risk of breast and ovarian cancer

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About This Question

Subject
Biology
Topic
Genetics and Oncology
Difficulty
Medium
Question Type
Multiple Choice

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