Genetic Screening for Cancer
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Genetic screening may be indicated for individuals who have a family history of which neoplasm? A) Leukemia B) Liver cancer C) Breast cancer D) Multiple myeloma
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Hello! Let's solve this question about genetic screening and family history of neoplasms.
Genetic screening and Family History
The question asks which of these neoplasms, or cancers, would indicate a need for genetic screening if there is a family history.
First, let's understand what genetic screening is used for in oncology.
Defining Genetic Screening
Genetic screening is used to identify individuals with an inherited predisposition to specific cancers.
Most cancers are sporadic, but some have strong hereditary links through specific gene mutations.
Let's evaluate our options one by one to see which is most commonly associated with hereditary syndromes.
| Option | Hereditary Link? |
|---|---|
| Leukemia | Rarely strictly hereditary |
| Liver cancer | Often linked to environmental factors |
| Breast cancer | Strong link via BRCA 1 and 2 |
| Multiple myeloma | Largely sporadic |
Breast cancer is one of the most well-known examples of a cancer with highly predictive genetic markers.
Focus: Breast Cancer
A family history of breast cancer often indicates testing for mutations in the BRCA 1 and BRCA 2 genes.
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