Contraindications for Beta-Blockers
Published:
Which condition is contraindicated for the use of beta-blockers like propranolol?
O Diabetes mellitus
O Hypertension
O Bronchial asthma
O Hyperlipidemia
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Step by Step Written Solution
In this problem, we are looking for the condition that is a contraindication for using beta blockers like propranolol.
Nursing Pharmacology Solution
First, let's look at propranolol specifically. It is a non selective beta blocker, meaning it blocks both beta one and beta two receptors.
Drug: Propranolol
- Non-selective Beta-blocker
- Blocks $\beta_1$ and $\beta_2$ receptors
Beta one receptors are primarily found in the heart. Blocking them slows the heart rate and reduces blood pressure. This is why beta blockers are often used to treat things like hypertension.
Receptor Review
However, beta two receptors are found in the lungs. Activating them causes bronchodilation, which opens the airways.
Because propranolol is non selective, it also blocks those beta two receptors in the lungs. This can lead to bronchoconstriction, narrowing the airways.
Blocking $\beta_2$ $\rightarrow$ Bronchoconstriction
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