Clinical Implication of Growth Fraction in Cancer
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A biopsy of a client's liver has been taken because there is suspicion that their lung cancer may have metastasized. The results confirm that there are cancerous cells in the client's liver and the oncologist has estimated a high growth fraction in the sample. The nurse should draw what implication from this finding?
A) A large proportion of the cells in the sample are actively dividing.
B) The doubling time of the mass is increasing.
C) Embryonic stem cells are present in the sample and represent a high risk for tumor growth.
D) The neoplastic cells in the tissue sample have achieved their maximum size.
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Step by Step Written Solution
Let's read the problem carefully together. A liver biopsy shows cancerous cells from lung cancer metastasis with a high growth fraction. We need to determine what a high growth fraction implies.
Understanding Tumor Growth Fraction
First, we must define what growth fraction actually means in biology. It is the ratio of proliferating cells to total cells in a tissue.
If a sample has a high growth fraction, it means that a large percentage of the total cell population is currently in the cell cycle, meaning they are actively dividing.
Let's analyze the options provided in the question. Option one says a large proportion of the cells in the sample are actively dividing. This perfectly matches our definition of a high growth fraction.
Evaluating Options
1. Large proportion of cells are actively dividing. ✅
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